Search found 32 matches

by tcphillips
Fri Jan 05, 2024 9:40 pm
Forum: GPU Projects and FahCores
Topic: FahCore 23 broken on Fedora 39
Replies: 52
Views: 583690

Re: FahCore 23 broken on Fedora 39

...I'll have to check the cost of an upgrade compared to the cost of the subsequent divorce settlement...

--Tom
by tcphillips
Fri Jan 05, 2024 3:18 pm
Forum: GPU Projects and FahCores
Topic: FahCore 23 broken on Fedora 39
Replies: 52
Views: 583690

Re: FahCore 23 broken on Fedora 39

Following this thread with interest...

I'm seeing the identical issue on an older Intel Quad core 6600 + GTX 750 running Ubuntu 22.04.
I'm wondering if the hardware combo is just plain too old.

Anybody else?

--Tom
by tcphillips
Fri Dec 08, 2023 6:09 pm
Forum: Scientific discussions (Non-FAH)
Topic: WSJ - FDA Approves World’s First Crispr Gene-Editing Drug for Sickle-Cell Disease
Replies: 0
Views: 26105

WSJ - FDA Approves World’s First Crispr Gene-Editing Drug for Sickle-Cell Disease

One wonders what portion of this F@H assisted with. --TCP FDA Approves World’s First Crispr Gene-Editing Drug for Sickle-Cell Disease Landmark decision heralds a new type of medicine that can tackle genetic conditions that are hard to treat By Joseph Walker Updated Dec. 8, 2023 11:45 am ET 23 Respon...
by tcphillips
Wed Oct 11, 2023 2:30 pm
Forum: The Science of FAH -- questions/answers
Topic: In Our Cellular Clocks, She’s Found a Lifetime of Discoveries (Protein folding) - Quanta Magazine
Replies: 0
Views: 66850

In Our Cellular Clocks, She’s Found a Lifetime of Discoveries (Protein folding) - Quanta Magazine

In Our Cellular Clocks, She’s Found a Lifetime of Discoveries For decades, Carrie Partch has led pioneering structural research on the protein clockwork that keeps time for our circadian rhythm. Is time still on her side? In her laboratory on the wooded campus of the University of California, Santa ...
by tcphillips
Tue Sep 19, 2023 7:28 pm
Forum: The Science of FAH -- questions/answers
Topic: WSJ - Google DeepMind’s AI Model Scours Our Genes to Guess Who Might Get Sick
Replies: 0
Views: 32536

WSJ - Google DeepMind’s AI Model Scours Our Genes to Guess Who Might Get Sick

Google DeepMind’s AI Model Scours Our Genes to Guess Who Might Get Sick By Jo Craven McGinty Updated Sept. 19, 2023 1:12 pm ET A machine-learning model evaluated 71 million variations in human proteins for their likelihood to cause disease One of the greatest challenges biologists face is figuring o...
by tcphillips
Mon Jul 03, 2023 4:34 pm
Forum: Scientific discussions (Non-FAH)
Topic: Mis-folded Protein Caused by Genetic Disease
Replies: 0
Views: 32630

Mis-folded Protein Caused by Genetic Disease

One Woman’s Race to Defuse the Genetic Time Bomb in Her Genes How DNA sequencing and new genetic drugs raise the chance we can cure any inherited disease. MIT Technology Review Antonio Regalado MIT Technology Review In 2011, Sonia Vallabh was handed a genetic report that contained a death sentence. ...
by tcphillips
Wed Mar 22, 2023 6:45 pm
Forum: Scientific discussions (Non-FAH)
Topic: WSJ - Scientists at DeepMind and Meta Press Fusion of AI, Biology
Replies: 0
Views: 10066

WSJ - Scientists at DeepMind and Meta Press Fusion of AI, Biology

‘AlphaFold was a huge advance in protein structure prediction…which led to a whole new wave of using deep learning,’ says computational biologist David Baker of the University of Washington By Steven Rosenbush March 22, 2023 10:30 am ET Meta Platforms Inc.’s new tool predicting the structure of hund...
by tcphillips
Thu Feb 03, 2022 9:44 pm
Forum: V7.6.x Public Release Windows/Linux/MacOS X
Topic: Guide for installing FAH v7.6.21 on Ubuntu 20.04.2 LTS v2
Replies: 13
Views: 16649

Solved --> installing FAH v7.6.21 on Ubuntu 20.04.2 LTS v

After following the guide, and a period in which 7.6.21 would not accept my passkey, it finally accepted my passkey and we're off and running. So the answer to my question below would appear to be "YES", the guide handles multiple GPUs, and "NO" there's no need for additional ins...
by tcphillips
Wed Sep 15, 2021 7:04 pm
Forum: Discussions of General-FAH topics
Topic: FAH Overall Rank
Replies: 42
Views: 50654

Re: FAH Overall Rank

Total score: 1,868,957,105 Total WU's: 97,305 Current Rank: EOC: 881 of 1730296 Years folding: 11.29.2007 Do you have dedicated 24/7 folding rigs? Yes, 3 desktops (that double as engineering and backup servers,) and one laptop (that should really be re-cycled.) Approximate cost per year in gear and ...
by tcphillips
Thu Feb 04, 2021 2:20 pm
Forum: The Science of FAH -- questions/answers
Topic: Are we doing any of this...?
Replies: 3
Views: 12187

Are we doing any of this...?

Some Proteins Change Their Folds to Perform Different Jobs Unusual proteins that can quickly fold into different shapes provide cells with a novel regulatory mechanism. Most proteins have only a single functional, folded configuration. But some can fold themselves into more than one shape to perfor...
by tcphillips
Tue Oct 06, 2020 11:02 pm
Forum: Issues with a specific WU
Topic: Bad work unit??
Replies: 36
Views: 5955

Re: Bad work unit??

Ach, I'm blind...thank you...
by tcphillips
Tue Oct 06, 2020 1:18 pm
Forum: Issues with a specific WU
Topic: Bad work unit??
Replies: 36
Views: 5955

Re: Bad work unit??

I've been following this thread and have a question. I have a 2 x GPU rig, 1 - GTX 1070 and 1 - GTX 950 The 1070 runs like a champ; it's the 950 that croaked off and "Failed". I see the recommended "--disable-cuda" in the Config screen. How, if it's possible, does one "shut ...
by tcphillips
Thu Jun 04, 2020 3:22 pm
Forum: Scientific discussions (Non-FAH)
Topic: What might this mean to F@H...?
Replies: 3
Views: 5380

Re: What might this mean to F@H...?

Indeed, to Bruce's point... "...OK with him to assume the external surface shape is a static fingerprint..." "...it wasn’t able to capture a phenomenon called induced fit: the way molecular surfaces change shape (and chemistry) when they get close to each other. In other words, the su...
by tcphillips
Wed Jun 03, 2020 5:37 pm
Forum: Scientific discussions (Non-FAH)
Topic: What might this mean to F@H...?
Replies: 3
Views: 5380

What might this mean to F@H...?

...from Quanta magazine... A Digital Locksmith Has Decoded Biology’s Molecular Keys Neural networks have been taught to quickly read the surfaces of proteins — molecules critical to many biological processes. The advance is already being used to create defenses for the virus responsible for COVID-19...
by tcphillips
Mon May 04, 2020 5:30 pm
Forum: Scientific discussions (Non-FAH)
Topic: Does any of this rub off on us...?
Replies: 1
Views: 4506

Does any of this rub off on us...?

Scientists Create Antibody That Defeats Coronavirus In Lab Tim Loh, Bloomberg Published 10:59 a.m. ET May 4, 2020 | Updated 11:03 a.m. ET May 4, 2020 Scientists created a monoclonal antibody that can defeat the new coronavirus in the lab, an early but promising step in efforts to find treatments and...