Search found 2 matches
- Fri Jun 02, 2017 5:40 am
- Forum: The Science of FAH -- questions/answers
- Topic: mTOR 2016 paper (rapamycin analog sensitivity prediction)
- Replies: 3
- Views: 2106
Re: mTOR 2016 paper (rapamycin analog sensitivity prediction
So you in a wet-lab you tested the activity of a wild-type mTOR and a number of mutant mTORs each in an environment with S6 kinase. And for mutants where activity was higher, you were able to look at structure difference versus wild-type via folding@home? (Used in a structure-prediction role?) From ...
- Thu Jun 01, 2017 5:01 am
- Forum: The Science of FAH -- questions/answers
- Topic: mTOR 2016 paper (rapamycin analog sensitivity prediction)
- Replies: 3
- Views: 2106
mTOR 2016 paper (rapamycin analog sensitivity prediction)
Came across the 2016 Chodera/Hsieh paper predicting mTOR mutant sensitivity to rapamycin analogues. Very nice work!
(I worked on mTOR (it had a different name back than) pathways for my thesis just under 20 years ago. Nice to see an old friend again.)
How did you use folding@home in this work?
(I worked on mTOR (it had a different name back than) pathways for my thesis just under 20 years ago. Nice to see an old friend again.)
How did you use folding@home in this work?