Folding Forum

Well ambitious maybe in the results, but shouldn't be anything particularly hard to implement, theory is all there - see e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637129/ We'll use it for most projects I anticipate, but not all. The adaptive schemes need a goal function - you have to choose...

Project 11726 now in ADVANCED! Stats: 11726: # atoms: 41312 credit: 11015 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed The SETDB1 protein methyltransferase is a putative epigenetic therapeutic target for a number of cancers, including melanoma, breast, colorectal, and prostate. Roles in...

Project 11720 now on FAH! Stats: 11720: # atoms: 23329 credit: 4879 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed The PRC2 complex is a therapeutic target for a number of cancers, currently undergoing clinical trials. It minimally consists of three proteins: EZH2, EED, and SUZ12. Its act...

Project 11720 now in ADVANCED! Stats: 11720: # atoms: 23329 credit: 4879 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed The PRC2 complex is a therapeutic target for a number of cancers, currently undergoing clinical trials. It minimally consists of three proteins: EZH2, EED, and SUZ12. It...

Projects 11718 and 11719 now in FAH! Stats: 11718: # atoms: 50119 credit: 15047 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed 11719: # atoms: 44691 credit: 12368 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed The PRC2 complex is a therapeutic target for a number of cancers, cu...

Projects 11718 and 11719 now in ADVANCED! Stats: 11718: # atoms: 50119 credit: 15047 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed 11719: # atoms: 44691 credit: 12368 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed The PRC2 complex is a therapeutic target for a number of cancer...

I understand that campus servers can be configured to drop pings, so the timeout messages are not necessarily indicative of the problem. They're dropping pings and traceroutes - you won't get anything from those. I wonder if an outgoing traceroute from the server 140.163.4.231 itself starts with th...

@ OntosChalmer - I restarted the WS an hour ago, and now we've rebooted the machines as well - would you mind seeing if the problems still persist?

@ OntosChalmer thanks a lot for the new report! I'm passing onto the networking folks to have them investigate further...

For now I've restarted the WS - which has been known to help temporarily.

Project 11715 now on FAH! Stats: 11715: # atoms: 12775 credit: 9858 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed This project is generating a test set for what we hope will increase the power of F@h by orders of magnitude, i.e. adaptive sampling. The idea is that instead of running many...

Hi folks - we've spoken to our networking people, no problems they can see - no errors or drops, plenty of bandwidth left (we're only doing 50mbps on a 10gbps port now). Pings and traceroutes are blocked from outside. Are you still experiencing problems? I'd like to get a sense of how many people ar...

Apologies, I've realized projects 11713 and 11714 have not had a thread here - adding now in case any problems still show up in the future. Stats: 11713 and 11714: # atoms: 35198 credit: 15965 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed Study of the biophysical effects of cancer mutati...

Project 11715 now in ADVANCED! Stats: 11715: # atoms: 12775 credit: 9858 k-factor: 0.75 timeout: 7d deadline: 10d precision: mixed This project is generating a test set for what we hope will increase the power of F@h by orders of magnitude, i.e. adaptive sampling. The idea is that instead of running...

We're investigating folks - thanks for reports!

@bruce might be related to today's connectivity issue then - interesting...