Folding Forum

Stats: # atoms: 35200 credit: 15965 k-factor: 0.75 timeout: 7d deadline: 10d 11707: Protein lysine methyltransferase SETD8, we have used Ensembler (http://ensembler.readthedocs.org/en/latest/) to generate models from all chains in all available crystal structures - 23 in total. This is the same prot...

Here we are simulating the NSD2 protein methyltransferase, a continuation of the Chodera Lab effort to map the conformational landscapes of all protein lysine methyltransferases - important epigenetic enzymes. This will provide powerful data for validations of existing chemical probes and inhibitors...

Projects 11703, 11704, 11705 moving into ADV! These are simulations of epigenetic enzymes - protein lysine methyltransferases NSD1 (11703), NSD3 (11704) and SETD2 (11705) using a new multisite Zn2+ ion model. Stats: k-factor is 0.75 for all of them Project 11703 base credit: 24051 timeout: 7d deadli...

Sorry guys, we were missing a MaxPacket>5 constraint on this work server / for 11703,4,5. Fixed now. Thanks for spotting the problem!