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FAH is working together with Rosetta?
Posted: Sat Jun 15, 2019 12:52 pm
by Jonazz
Hey all. After a while of not folding I decided to give it another go. One of the projects assigned to me talked about cooperation with the Baker Lab. You know, the lab behind Rosetta@Home!
So does this mean that both projects are actively working together?
Link to the projects:
https://apps.foldingathome.org/project?p=14140
Re: FAH is working together with Rosetta?
Posted: Sat Jun 15, 2019 5:06 pm
by toTOW
In this case, Rosetta is a kind of brute force study that doesn't go very in deep of what happens, so they use it to select the best candidates that are then studied more deeply on FAH.
Re: FAH is working together with Rosetta?
Posted: Wed Jun 26, 2019 4:28 pm
by gbowman
There are lots of opportunities for collaboration. Rosetta is one of the best ways to design a protein to adopt a specific conformation. Folding@home is one of the best ways to understand how the protein adopts that conformation, and what sort of motions it undergoes once folded. The Voelz lab has struck up a nice collaboration drawing on both approaches.
Re: FAH is working together with Rosetta?
Posted: Fri Jun 28, 2019 10:57 am
by JimF
gbowman wrote:The Voelz lab has struck up a nice collaboration drawing on both approaches.
Wonderful. I have supported both for years, and noticed the interesting joint project descriptions. And I am not far from Temple U., so can get them hot off the press.