Research on sclerosis?

Moderators: Site Moderators, PandeGroup

Research on sclerosis?

Postby iceman1992 » Fri May 18, 2012 3:39 pm

Did FAH ever conduct research on sclerosis (ALS, MS, PLS)? It's not on the diseases studied page. I'm wondering if it had previously been studied. Sclerosis seem to be connected with misfolded proteins to some degree (at least some of them).
iceman1992
 
Posts: 381
Joined: Fri Mar 23, 2012 5:16 pm

Re: Research on sclerosis?

Postby Jesse_V » Fri May 18, 2012 5:08 pm

The term does not occur on folding.stanford.edu nor on folding.typepad.com so IMO its reasonable to assume that no, it does not. And who said sclerosis was affected by protein misfolding? The publication "Neuroligin Trafficking Deficiencies Arising from Mutations in the a/β-Hydrolase Fold Protein Family" in part ties protein misfolding in with autism, but to my knowledge F@h hasn't directly researched that either. However, that doesn't necessarily mean that F@h hasn't impact MS or autism, or tons of other diseases that aren't listed on the Diseases FAQ. Given the amount of times each of the publications from F@h is cited in the scientific community, perhaps one day cures will be found for these diseases based on the foundation of research laid down by F@h and other scientific groups.

Using Google, I found this thread on MS and F@h: viewtopic.php?f=17&t=14726
Pen tester at Cigital/Synopsys
User avatar
Jesse_V
 
Posts: 2773
Joined: Mon Jul 18, 2011 4:44 am
Location: USA

Re: Research on sclerosis?

Postby iceman1992 » Mon May 21, 2012 1:55 pm

Jesse_V wrote:The term does not occur on folding.stanford.edu nor on folding.typepad.com so IMO its reasonable to assume that no, it does not. And who said sclerosis was affected by protein misfolding? The publication "Neuroligin Trafficking Deficiencies Arising from Mutations in the a/β-Hydrolase Fold Protein Family" in part ties protein misfolding in with autism, but to my knowledge F@h hasn't directly researched that either. However, that doesn't necessarily mean that F@h hasn't impact MS or autism, or tons of other diseases that aren't listed on the Diseases FAQ. Given the amount of times each of the publications from F@h is cited in the scientific community, perhaps one day cures will be found for these diseases based on the foundation of research laid down by F@h and other scientific groups.

Using Google, I found this thread on MS and F@h: viewtopic.php?f=17&t=14726
Sorry for the late reply Jesse_V, was out of town a few days.
I found this publication http://www.ncbi.nlm.nih.gov/pubmed/18097159
Yes from what I understand research results about a particular disease can be used in other diseases too?
iceman1992
 
Posts: 381
Joined: Fri Mar 23, 2012 5:16 pm


Return to The Science of FAH -- questions/answers

Who is online

Users browsing this forum: No registered users and 2 guests

cron