Protein vibrations?

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Protein vibrations?

Postby P5-133XL » Fri Jan 17, 2014 5:58 am

I just read http://www.sciencedaily.com/releases/2014/01/140116084838.htm. It would seem to me that such vibrations would significantly affect folding. Further that different folding shapes could produce different resonant frequencies that may be characteristic and testable. Also a simulator, like F@H, that uses atomic forces would be a good way to predict such interactions.
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Re: Protein vibrations?

Postby bruce » Fri Jan 17, 2014 6:23 am

Science question:

I don't suppose that anybody has looked at the spectrum of a protein in vitro and compared it to the spectrum in silico?
Just how good are our models?
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Re: Protein vibrations?

Postby VijayPande » Fri Jan 17, 2014 4:12 pm

This is a pretty new technique. It's hard for me to tell how useful it will be, but it's definitely interesting. And new types of experiments can be very powerful additions to the weapons we can bring to bear on a problem.
Prof. Vijay Pande, PhD
Departments of Chemistry, Structural Biology, and Computer Science
Chair, Biophysics
Director, Folding@home Distributed Computing Project
Stanford University
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