P45, Q6600 & 2x GTX260 216's.
I used to to have the 260's folding on Ubuntu 9.04 with the 180.60 driver but been using Windows for a while.
I think I may have messed up at bit when I copied the client folders. but basically I followed the headless guide from step 10. Using the latest Nvidia repo, the 2.3 Toolkit & the WINE version from the Ubuntu repo which is the same as recommended in this thread.
I did run in trouble with the Wine wrapper, the link in the guide failed so I used a link from the 'new v2.1 wrapper imminent' thread, the newer version - http://www.hyperchronos.org/cudart.dll.so
I'm using the -GPU 0 & -GPU 1 flags but as I said last night the primary card was running very slowly. Going to have another go & will report back. The only reason I've switched back to Linux is due to the new A3 WUs performing so poorly using the 2.19 core. Now the Windows core has also been updated I'd be better back on the dark side for the GPU's & CPU combined but it would be nice to have both setups available.