Did FAH Play A Role In This Promising Development?

Moderators: Site Moderators, PandeGroup

Did FAH Play A Role In This Promising Development?

Postby Alan C. Lawhon » Wed Sep 24, 2014 11:22 pm

http://phys.org/news/2014-09-scientists ... tml#ajTabs

The article mentions how millions of bioengineered DNA protein variants were tested before they homed in on the decoy protein which demonstrated the greatest affinity for binding to the Gas6 protein - thus greatly reducing metastasis in mice. You don't go looking through "millions" of candidates manually, (or I don't think you do ...), so this seems highly suggestive [to me] that an automated process was used. Since Dr. Cochran and Dr. Giaccia's research involves proteins, I wonder if some of the work units we've been crunching have been runs, clones and gens of projects directly supporting this work?

Hopefully, when the trials and testing move from animals to humans, this new approach won't turn out to be another dead end.
Alan C. Lawhon
Posts: 97
Joined: Thu Dec 20, 2012 3:58 am

Re: Did FAH Play A Role In This Promising Development?

Postby VijayPande » Thu Sep 25, 2014 1:14 am

This is great work, but the WUs didn't support this particular project. We do have a lot going on in cancer in general right now.
Prof. Vijay Pande, PhD
Departments of Chemistry, Structural Biology, and Computer Science
Chair, Biophysics
Director, Folding@home Distributed Computing Project
Stanford University
User avatar
Pande Group Member
Posts: 2651
Joined: Fri Nov 30, 2007 6:25 am
Location: Stanford

Return to The Science of FAH -- questions/answers

Who is online

Users browsing this forum: No registered users and 1 guest